Risk of Heart Failure-related Events in Patients Exposed to Medical Cannabis: A Longitudinal Cohort Study

Abstract Objective: This study examined the association between the authorized prescription of cannabis and heart failure (HF) events. Study design: We conducted a retrospective cohort study of patients who received an authorized prescription of cannabis in Ontario cannabis clinics between 2014-2019 and controls selected from the general population of Ontario. Methods: Ontario’s health administrative data and clinical data from the cannabis clinics were used. Inverse probability of treatment weights based on propensity scores were used to minimize confounding between cannabis