Sex‐specific ethylene responses drive floral sexual plasticity in Cannabis sativa

Abstract Cannabis sativa L. exhibits pronounced sexual plasticity in which both XX and XY plants can undergo floral phenotypic sex reversal in response to ethylene modulation, yet the underlying molecular mechanisms remain poorly defined. Here, we present the most extensive multi‐omic analysis of ethylene‐induced sex change in C. sativa to date, integrating over 130 RNA‐seq libraries, ethylene pathway metabolite quantification, and whole‐genome sequencing across three XX and XY genotypes. Treatments with silver thiosulfate and ethephon induced more than 80% phenotypic