Dose- and tissue-dependent effects of cannabidiol on antioxidant status in developing chicken embryos
Abstract This study investigated the dose- and tissue-dependent effects of cannabidiol (CBD) on the antioxidant status of developing chicken embryos, a key model for vertebrate development. Fertilized eggs were administered CBD (2, 10, or 20 mg/kg egg weight) on the sixth day of incubation. Tissues (brain, liver, heart, thigh muscle, intestine) were collected on day 13 and analyzed for glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD), and malondialdehyde (MDA). The results demonstrated potent, tissue-specific effects. CBD exhibited its strongest
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