Suicide attempt and paranoia persisting for 28 days following heavy delta‐9‐tetrahydrocannabinolic acid and tetrahydrocannabinol use: A case report

Abstract Background: Cannabis contains various cannabinoids, with Δ9‐tetrahydrocannabinol (Δ9‐THC) being the primary psychoactive compound. A non‐psychoactive precursor called Δ9‐tetrahydrocannabinolic acid (THC‐A) is converted to Δ9‐THC slowly over time or rapidly when heated. Cannabis use is linked to psychotic outcomes, with increased risk associated with heavier or earlier use. Additionally, Δ9‐THC’s lipophilic nature leads to prolonged detection following heavy use. These factors highlight the need for a better understanding of cannabis formulations, dosing, and their psychiatric and pharmacokinetic implications. Case Presentation: