Multi-ancestry genetic architecture of sleep duration and its relationship to other sleep and psychiatric phenotypes

Abstract Differences in sleep duration, quality, and timing are associated with variation in cognition, health outcomes, and quality of life. Genetic studies may help explain the underlying mechanisms of sleep and its relationships to other conditions. Our previous work highlighted risk loci associated with short (<6hrs) and long sleep (>9hrs), using data from the UK Biobank and the Million Veteran Program. We build on this work by conducting a genome wide association study (GWAS) and multi-ancestry meta-analysis of sleep duration