Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

Abstract Aims: We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods: Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (medications or nondrug substances [NDS]) to identify subject clusters. Results: A total of 1544 spontaneous reports were analysed, comprising mainly boys (65.6%), aged on average 16 ± 1 years. Four clusters