Cutaneous targets for topical pain medications in patients with neuropathic pain: individual differential expression of biomarkers supports the need for personalized medicine

Abstract Supplemental Digital Content is Available in the Text. Biomarker analysis of postherpetic neuralgia patient skin biopsies demonstrates individual differences among receptors for neuroactive topical agents among keratinocytes, demonstrating novel potential mechanisms of action. Article type: Research Article Keywords: Keratinocyte, Immunochemistry, Skin, Cannabinoid, CGRP, PHN Authors: Phillip J. Albrecht ⚬, Yi Liu, George Houk, Beth Ruggiero, Daniel Banov, Marilyn Dockum, A.J. Day, Frank L. Rice, Gus Bassani Affiliations: Integrated Tissue Dynamics, LLC (INTiDYN), Rensselaer, NY, USA; Professional Compounding Centers of