Dronabinol
Patients will take one 10 mg dose of Dronabinol.
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To investigate the effects of Dronabinol use on blood pressure and neurovascular physiology
Locally preserved from ClinicalTrials.govOpen ClinicalTrials.govlast source update 2026-09-11
What this record can show
This locally preserved record separates the registered protocol from source-reported registry results. Neither is a treatment recommendation.
Registry facts
Linked local records
Local links use governed condition terms or exact source-reported intervention names. They are navigation candidates, not efficacy claims.
Interventions
Patients will take one 10 mg dose of Dronabinol.
Patients will take one 10mg dose of a Placebo Pill.
Eligibility
primary outcomes
Time frame: Baseline, 30 days
Blood pressure is the force exerted by circulating blood on the walls of the arteries as it is pumped through the body. Blood pressure will be measured as a ratio of systolic/diastolic (mmHg).
Time frame: Baseline, 30 days
Heart Rate is the number of contractions (beats) that the heart makes per minute. This will be measured in bpm (beats per minute)
secondary outcomes
Time frame: Baseline, 30 days
Baroreflex sensitivity will be assessed using beat-by-beat blood pressure, heart rate, and Sympathetic nerve activity collected continuously for at least 5min. This will be measured in ms/mmHg.
Time frame: Baseline, 30 days
Sympathetic control will be measured by microneurography of peroneal or fibular nerve, reported as bursts of sympathetic activity per minute or normalized to 100 heart beats
Time frame: Baseline, 30 days
Flow Mediated Dilation will be measured by ultrasonography of brachial artery, reported as an absolute change in arterial diameter from resting baseline
Time frame: Baseline, 30 days
Aortic Wave Reflection will be measured via arterial tonometry, reported as aortic augmentation index
Publications
No exact PMID-linked public article is currently readable locally.