OBSERVATIONALCOMPLETEDNCT01647425
Prevalence and Risk Factors for Persistent Tobacco or Alcohol Use Over the First Year of a First Lung or Head and Neck Cancer
This is an multicenter study for preventive and therapeutic strategies for patients with head and neck cancer
Locally preserved from ClinicalTrials.govOpen ClinicalTrials.gov↗last source update 2026-03-16
What this record can show
Protocol only - no registry results posted
This locally preserved record separates the registered protocol from source-reported registry results. Neither is a treatment recommendation.
Registry facts
Study at a glance
- Phase
- Not reported
- Enrollment
- 385 (ACTUAL)
- Start date
- 2012-04
- Sponsor
- Centre Oscar Lambret
- Design
- Not reported
- Locations
- 3
- Results record
- Not present in registry snapshot
Continuing the chronic intoxication by either tobacco or alcohol after the initial diagnosis of a first lung or head and neck cancer significantly improves the risk of experiencing a second cancer, and largely affects the long term survival. Addiction intervention programs should be personalized according to the patient's profile, with the aim to develop more sustained intervention and monitoring in patients identified at higher risk of not spontaneously stopping harmful substance use. As of today, the trajectories of smoking and drinking habits and the risk factors for persisting smoking or drinking habits have been insufficiently explored among patients with a first lung or head and neck cancer. The ALTAK study aims to depict the rate of tobacco smokers 12 months after the initial diagnosis of a first lung or head and neck cancer. The secondary objectives of the study are: * to depict the rate of alcohol users 12 months after the initial diagnosis of a H\&N cancer * to depict the rate of tobacco smokers at cancer diagnosis * to depict the rate of alcohol users at cancer diagnosis * to determine the social, motivational, psychiatric, tobacco-related, alcohol-related, and cannabis-related features associated with stopping tobacco in the year following the diagnosis of a first TARC. * to determine the social, psychiatric, tobacco-related, alcohol-related, and cannabis-related features associated with stopping alcohol drinking in the year following the diagnosis of a first H\&N cancer
Head and Neck CancerLung Cancerhead and neck cancerlung cancertobacco use disorderalcoholism
Linked local records
Related local records
Local links use governed condition terms or exact source-reported intervention names. They are navigation candidates, not efficacy claims.
Conditions
No published condition report matched.
Cannabinoids and active compounds
No governed compound link was found.
Medicines
No exact medicine-name link was found.
Research network
Researchers and organizations
Interventions
What was registered
BEHAVIORALphysician assessment
* Socio-economic conditions and general features: educational level, professional status... * Assessment of current and past use of tobacco: current smoking status reported by the patient; in lifelong non-smokers: previous history of passive smoking reported by the patient; breath carbon monoxide level; in past smokers: age of first cigarette, total reported duration of active smoking, breath carbon monoxide level... * in current smokers: age of first tobacco use, total reported duration of active smoking; Fagerström Nicotine Dependence Test... * Assessment of the current and past uses of alcohol: previous-year assessment using the CAGE questionnaire and the AUDIT Test; average weekly alcohol consumption over the last 12 months... * Assessment of current use of cannabis using the Cannabis Abuse Screening Test * Psychiatric assessment using the MINI 5.0
Eligibility
Population and criteria
- Sex
- ALL
- Minimum age
- 18 Years
- Maximum age
- Not reported
- Healthy volunteers
- Not accepted
Study population
patient with a first head and neck cancer or first lung cancer
Inclusion criteria
- first head and neck or lung cancer
- first support
- age ≥ 18
- patient covered by health insurance
- signed informed consent
Exclusion criteria
- prior lung or head and neck cancer
- History of another cancer \<5 years, not evolutive and untreated at baseline (carcinoma of the cervix, or basal cell carcinoma of the skin properly treated are allowed). The presence of a second discovery tumor location at the same time as the lung or head and neck cancer, is not a criteria for non-inclusion
- mesothelioma and oesophageal cancer
- unable to undergo trail medical follow up (geographical, social and psychological reasons)
- pregnant or nursing women
- patient under guardianship
primary outcomes
primary measures
tobacco consumption
Time frame: at 12 months
reported tobacco smoking
secondary outcomes
secondary measures
tobacco smoking
Time frame: at baseline, 3 and 6 months
frequency tobacco consumption
alcohol drinking
Time frame: at baseline, 3, 6 and 12 months
frequency of alcohol consumption
progression free survival
Time frame: at 12 months
median time between date of inclusion and date of first progression
overall survival
Time frame: at 12 months
median time between date of inclusion and date of death
sociodemographic, cancer-related, tobacco-related, alcohol-related, and psychiatric characteristics
Time frame: at baseline
Publications
Locally readable linked articles
1linked publicationBMC Cancer · Free full text Snapshot provenance
- Snapshot
- dc35d08a-a0ab-4299-bc89-d6b28705cfc0
- Retrieved
- 11/09/2026, 14:15:46
- SHA-256
- dd27d312d9ed57e12b3f09e3f64c12548d4d3497bdef5cf4699ef172e0bf2a26