INTERVENTIONALCOMPLETEDNCT00636766
Atherosclerotic Plaque Texture-Experimental and Clinical Study on the Diagnostic and Therapeutic Strategies of Atherosclerotic Plaque Vulnerability
The aim of the present study is to examine the atherosclerotic plaque stability using in vivo and in vitro techniques and to investigate the influence of exercise, anti-diabetic, lipid-lowering and cannabinoids receptor antagonists on atherosclerotic plaque texture in patients with cardiovascular risk and animals prone to atherosclerosis.
Locally preserved from ClinicalTrials.govOpen ClinicalTrials.gov↗last source update 2012-11-02
What this record can show
Protocol only - no registry results posted
This locally preserved record separates the registered protocol from source-reported registry results. Neither is a treatment recommendation.
Registry facts
Study at a glance
- Phase
- NA
- Enrollment
- 300 (ACTUAL)
- Start date
- 2005-09
- Sponsor
- Aristotle University Of Thessaloniki
- Design
- RANDOMIZED · FACTORIAL
- Locations
- 1
- Results record
- Not present in registry snapshot
Carotid AtherosclerosisStrokeType 2 DiabetesMetabolic Syndromecardiovascular events
Linked local records
Related local records
Local links use governed condition terms or exact source-reported intervention names. They are navigation candidates, not efficacy claims.
Conditions
No published condition report matched.
Cannabinoids and active compounds
No governed compound link was found.
Medicines
No exact medicine-name link was found.
Interventions
What was registered
DRUGatorvastatin
A:Experimental study of atherosclerosis B1:Effects of exercise on experimental atherosclerosis B2:Effects of exercise on high risk patients C1:Effects of statins on atherosclerotic plaque stability (experimental) C2:Effects of statins on atherosclerotic plaque stability (clinical) D:Effects of rosiglitazone and metformin on cardiovascular risk factors E:Effects of rimonabant on atherosclerotic plaque stability (experimental)
DRUGrimonabant
A:Experimental study of atherosclerosis B1:Effects of exercise on experimental atherosclerosis B2:Effects of exercise on high risk patients C1:Effects of statins on atherosclerotic plaque stability (experimental) C2:Effects of statins on atherosclerotic plaque stability (clinical) D:Effects of rosiglitazone and metformin on cardiovascular risk factors E:Effects of rimonabant on atherosclerotic plaque stability (experimental)
DRUGrosiglitazone
A:Experimental study of atherosclerosis B1:Effects of exercise on experimental atherosclerosis B2:Effects of exercise on high risk patients C1:Effects of statins on atherosclerotic plaque stability (experimental) C2:Effects of statins on atherosclerotic plaque stability (clinical) D:Effects of rosiglitazone and metformin on cardiovascular risk factors E:Effects of rimonabant on atherosclerotic plaque stability (experimental)
DRUGmetformin
A:Experimental study of atherosclerosis B1:Effects of exercise on experimental atherosclerosis B2:Effects of exercise on high risk patients C1:Effects of statins on atherosclerotic plaque stability (experimental) C2:Effects of statins on atherosclerotic plaque stability (clinical) D:Effects of rosiglitazone and metformin on cardiovascular risk factors E:Effects of rimonabant on atherosclerotic plaque stability (experimental)
Eligibility
Population and criteria
- Sex
- ALL
- Minimum age
- 50 Years
- Maximum age
- 80 Years
- Healthy volunteers
- Accepted
Inclusion criteria
- Carotid atherosclerosis
- Femoral atherosclerosis
- Cardiovascular risk
Exclusion criteria
- Heart failure
- Renal disease
- Liver disease
- Life-threatening diseases
primary outcomes
primary measures
Ultrasound and immunohistochemical parameters of plaque stability; novel cardiovascular risk factors
Time frame: 3 years
secondary outcomes
secondary measures
Long-term cardiovascular outcomes
Time frame: 3 years
Publications
Locally readable linked articles
0No exact PMID-linked public article is currently readable locally.
Snapshot provenance
- Snapshot
- f1f694d4-fb60-414f-810f-104a1fab28f3
- Retrieved
- 11/09/2026, 14:54:28
- SHA-256
- d0a6298d02ed0a826e4e528064f1ec3c001c6d713123615e24176b329712e680