A pan-cancer analysis revealing the role of TIGIT in tumor microenvironment
Abstract T cell immunoreceptor with immunoglobulin and ITIM domain (TIGIT), an immune checkpoint, plays a pivotal role in immune suppression.…
Abstract T cell immunoreceptor with immunoglobulin and ITIM domain (TIGIT), an immune checkpoint, plays a pivotal role in immune suppression.…
Abstract Recent studies have shown that PPP1R14B was highly expressed in tumor tissues and patients with high expression of PPP1R14B…
Abstract DNA methylation patterns are essential in understanding carcinogenesis. However, the relationship between DNA methylation and the immune process has…
Abstract Background: CD161 is a promising immune checkpoint mainly expressed on natural killer (NK) cells and is essential for immunoregulatory…
Keywords: CDF, cumulative distribution function, CGGA, Chinese Glioma Genome Atlas, CNA, copy number alternations, CNV, copy number variation, CSF-1, colony-stimulating…
Abstract Background: Immunotherapy has significantly improved patient outcomes, but encountered obstacles recently. CD96, a novel immune checkpoint expressed on T…