Cancer cachexia: molecular basis and therapeutic advances
Abstract The dynamic interplay between neoplastic cells and the host has been increasingly recognized as important players in the pathogenesis…
Zhi-Bin Wang
Pan-cancer analyses identify DCBLD2 as an oncogenic, immunological, and prognostic biomarker
Abstract Discoidin, CUB, and LCCL domain-containing protein 2 (DCBLD2) is a two-domain transmembrane protein-coding gene located on chromosome 3, the…
A collagen-binding EGFR antibody fragment targeting tumors with a collagen-rich extracellular matrix
Abstract Many tumors over-express collagen, which constitutes the physical scaffold of tumor microenvironment. Collagen has been considered to be a…