Pan‐Cancer analyses of Necroptosis‐Related genes as a potential target to predict immunotherapeutic outcome
Abstract Necroptosis is a unique programmed death mechanism of necrotic cells. However, its role and specific mechanism in cancer remain…
Zheng Zhou
A systematic pan-cancer analysis of PXDN as a potential target for clinical diagnosis and treatment
Abstract Peroxidasin (PXDN), also known as vascular peroxidase-1, is a newly discovered heme-containing peroxidase; it is involved in the formation…
A Systematic Pan-Cancer Analysis of CASP3 as a Potential Target for Immunotherapy
Abstract CASP3 is the gene encoding caspase-3, a specific protease that cleaves substrates such as poly-ADP ribose polymerase and acetyl-DEVD-7-amino-4-methylcoumarin.…
Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3
Abstract The centromere is a unique chromosomal locus that ensures accurate segregation of chromosomes during cell division by directing the…