Replication Stress Defines Distinct Molecular Subtypes Across Cancers
Abstract Significance: We develop a transcriptional profile of replication stress which characterizes replication stress and its cellular response, revealing phenotypes…
Yves Pommier
Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage
Abstract Tyrosyl DNA phosphodiesterase 2 (TDP2) is a multifunctional protein implicated in DNA repair, signal transduction and transcriptional regulation. In…