Temporal-iCLIP captures co-transcriptional RNA-protein interactions
Abstract Dynamic RNA-protein interactions govern the co-transcriptional packaging of RNA polymerase II (RNAPII)-derived transcripts. Yet, our current understanding of this…
Yuhui Dou
Affinity proteomic dissection of the human nuclear cap-binding complex interactome
Abstract A 5′,7-methylguanosine cap is a quintessential feature of RNA polymerase II-transcribed RNAs, and a textbook aspect of co-transcriptional RNA…
NCBP3 positively impacts mRNA biogenesis
Abstract The nuclear Cap-Binding Complex (CBC), consisting of Nuclear Cap-Binding Protein 1 (NCBP1) and 2 (NCBP2), associates with the nascent…