AEBP1 promotes papillary thyroid cancer progression by activating BMP4 signaling
Abstract AEBP1 promotes growth, and migration of PTC cells in vitro and in vivo. AEBP1 induces epithelial-mesenchymal transition in PTC…
Yongjun Liang
Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside
Abstract Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a pivotal enzyme in lipid metabolism and a revolutionary therapeutic…
Identification and Validation of a Prognostic Signature Based on Methylation Profiles and Methylation-Driven Gene DAB2 as a Prognostic Biomarker in Differentiated Thyroid Carcinoma
Abstract Recurrence is the major death cause of differentiated thyroid carcinoma (DTC), and a better understanding of recurrence risk at…
Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancer
Abstract Background: Inhibitors of apoptosis proteins (IAPs) are a family of antiapoptotic proteins modulating cell cycle, signal transduction and apoptosis.…