Bipiperidinyl Derivatives of Cannabidiol Enhance Its Antiproliferative Effects in Melanoma Cells
Abstract Cannabis and its major cannabinoid cannabidiol (CBD) are reported to exhibit anticancer activity against skin tumors. However, the cytotoxic…
Xiaozhen Zhang
Integrative Analysis of Proteome-wide Association Studies and Functional Enrichment Analysis to Identify Genes and Chemicals Associated with Alcohol Dependence
Abstract Methods: Using data from published alcohol dependence genome-wide association studies, we first conducted a proteome-wide association study of alcohol…
O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy
Abstract O-linked β-d-N-acetylglucosamine (O-GlcNAc) is an important post-translational modification of serine or threonine residues on thousands of proteins in the…
Specific Isolation of Clostridium botulinum Group I Cells by Phage Lysin Cell Wall Binding Domain with the Aid of S-Layer Disruption
Abstract Clostridium botulinum is a notorious pathogen that raises health and food safety concerns by producing the potent botulinum neurotoxin…
RCAN1-mediated calcineurin inhibition as a target for cancer therapy
Abstract Cancer is the leading cause of mortality worldwide. Regulator of calcineurin 1 (RCAN1), as a patent endogenous inhibitor of…
Sorption of carbendazim on activated carbons derived from rape straw and its mechanism†
Abstract Due to the production and widespread application of pesticides, pesticide pollution poses a potential danger to human health and…