Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists
Abstract We report a blueprint for the rational design of G protein coupled receptor (GPCR) ligands with a tailored functional…
Xiaoting Li
Structural basis of selective cannabinoid CB2 receptor activation
Abstract Cannabinoid CB2 receptor (CB2R) agonists are investigated as therapeutic agents in the clinic. However, their molecular mode-of-action is not…