Abstract Background: The APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family plays a vital mutagenic role in diverse human…
Abstract Purpose: The objective of this study was to develop and evaluate a novel classifier and prognostic model based on…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-87059-8. Article type: Research Article Keywords: Programmed cell death,…
Abstract Background: BRAFV600E is the most common genetic mutation in differentiated thyroid cancer (DTC) occurring in 60% of patients and…
Abstract MAPK pathway-driven tumorigenesis, often induced by BRAFV600E, relies on epithelial dedifferentiation. However, how lineage differentiation events are reprogrammed remains…
Abstract Background: Thyroid cancer represents the most prevalent malignant endocrine tumour, with rising incidence worldwide and high mortality rates among…
Abstract MAPK signaling inhibitor (MAPKi) therapies show limited efficacy for advanced thyroid cancers despite constitutive activation of the signaling correlates…
Abstract Objective: Large volume radiological text data have been accumulated since the incorporation of electronic health record (EHR) systems in…
Abstract Thyroid cancer (THCA) is a heterogeneous disease with multiple clinical outcomes Immune cells regulate its progression. Three immunomolecular subtypes…