Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-04949-7. Article type: Research Article Keywords: Common bile duct…
Abstract Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, and patients with the BRAFV600E mutation often…
Abstract T-cell therapies based on chimeric antigen receptor (CAR) targeting of a tumor-specific antigen offer hope for patients with relapsed…
Abstract Background: Leptin receptor overlapping transcript (LEPROT) is reported to be involved in metabolism regulation and energy balance as well…
Abstract Regulated proteolysis by proteasomes involves ~800 enzymes for substrate modification with ubiquitin, including ~600 E3 ligases. We report here…
Abstract Tyrosyl DNA phosphodiesterase 2 (TDP2) is a multifunctional protein implicated in DNA repair, signal transduction and transcriptional regulation. In…