William Hind

February 1, 2024

Cannabidiol reduces intraventricular hemorrhage brain damage, preserving myelination and preventing blood brain barrier dysfunction in immature rats

Abstract Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. This…

May 4, 2023

Effects of Cannabidiol, Hypothermia, and Their Combination in Newborn Rats with Hypoxic-Ischemic Encephalopathy

Abstract Therapeutic hypothermia is well established as a standard treatment for infants with hypoxic-ischemic (HI) encephalopathy but it is only…

June 6, 2022

Cannabidiol Reduces Inflammatory Lung Damage After Meconium Aspiration in Newborn Piglets

Abstract Aim: To assess the effects of cannabidiol (CBD) on lung damage in a piglet model of meconium aspiration syndrome…

March 8, 2022

Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis

Abstract The innate immune response to bacterial and viral molecules involves the coordinated production of cytokines, chemokines, and type I…

January 18, 2021

Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity

Abstract Background and Purpose: Cannabidiol (CBD) has been shown to differentially regulate the mechanistic target of rapamycin complex 1 (mTORC1)…

September 26, 2019

Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats

Abstract Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects…