Longitudinal study of risk factors predicting cannabis use disorder in UK young adults and adolescents
Abstract Background: Cannabis use disorder (CUD) affects up to 1 in 5 people who try cannabis. In order to develop…
Will Lawn
Value signals guiding choices for cannabis versus non-drug rewards in people who use cannabis near-daily
Abstract Rationale: Despite the critical role of choice processes in substance use disorders, the neurobehavioral mechanisms guiding human decisions about…
Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks
Abstract Adolescence is a time of rapid neurodevelopment and the endocannabinoid system is particularly prone to change during this time.…
Persistent increased severity of cannabis use disorder symptoms in adolescents compared to adults: a one-year longitudinal study
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-024-01806-y. Article type: Research Article Keywords: Cannabis use disorder,…
The acute effects of cannabis, with and without cannabidiol, on attentional bias to cannabis related cues: a randomised, double-blind, placebo-controlled, cross-over study
Abstract Rationale: Attentional bias to drug-related stimuli is hypothesised to contribute towards addiction. However, the acute effects of Δ9-tetrahydrocannabinol (THC)…
Assessing Cannabis Use in People with Psychosis
Abstract Introduction: Cannabis use is common in people with psychotic disorders and is associated with the exacerbation of symptoms, poor…
Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry
Abstract Rationale: Cannabis-based medicinal products (CBMPs) have been identified as novel therapeutics for generalised anxiety disorder (GAD) based on pre-clinical…
The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double‐blind, placebo‐controlled, crossover experiment
Abstract Background and Aims: Long‐term harms of cannabis may be exacerbated in adolescence, but little is known about the acute…
The CannTeen Study: Cannabis use disorder, depression, anxiety, and psychotic-like symptoms in adolescent and adult cannabis users and age-matched controls
Abstract Background: Adolescence is characterised by psychological and neural development. Cannabis harms may be accentuated during adolescence. We hypothesised that…
Individual and combined effects of cannabidiol and Δ9-tetrahydrocannabinol on striato-cortical connectivity in the human brain
Abstract Background: Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the two major constituents of cannabis with contrasting mechanisms of action. THC…