Potential Therapeutic Targets to Modulate the Endocannabinoid System in Alzheimer’s Disease
Abstract Alzheimer’s disease (AD), the most common neurodegenerative disease (NDD), is characterized by chronic neuronal cell death through progressive loss…
Tommaso Cassano
Hexahydrocannabinol Pharmacology, Toxicology, and Analysis: The First Evidence for a Recent New Psychoactive Substance
Abstract Background: During the last two years, hexahydrocannabinol (HHC), the hydrogenated derivative of tetrahydrocannabinol has been freely sold by internet…
New Psychoactive Substances Intoxications and Fatalities during the COVID-19 Epidemic
Abstract Simple Summary: We presented a comprehensive, systematic literature review of all published New Psychoactive Substances (NPS)-related intoxications and fatalities…
Pharmacological and Toxicological Effects of Phytocannabinoids and Recreational Synthetic Cannabinoids: Increasing Risk of Public Health
Abstract Synthetic Cannabinoids (CBs) are a novel class of psychoactive substances that have rapidly evolved around the world with the…
From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases
Abstract Cannabis sativa, commonly known as marijuana, contains a pool of secondary plant metabolites with therapeutic effects. Besides Δ9-tetrahydrocannabinol that…
Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target
Abstract As a consequence of an increasingly aging population, the number of people affected by neurodegenerative disorders, such as Alzheimer’s…