Methylomic signature of current cannabis use in two first-episode psychosis cohorts
Abstract The rising prevalence and legalisation of cannabis worldwide have underscored the need for a comprehensive understanding of its biological…
Tom P. Freeman
Detection and quantification of synthetic cannabinoids in seven illicitly sourced disposable vapes submitted by an individual presenting to a UK drug and alcohol service
Abstract Background and aims: In the United Kingdom and internationally, synthetic cannabinoids (SCs) are a common adulterant in illicitly sourced…
Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks
Abstract Adolescence is a time of rapid neurodevelopment and the endocannabinoid system is particularly prone to change during this time.…
Applying machine learning to international drug monitoring: classifying cannabis resin collected in Europe using cannabinoid concentrations
Abstract In Europe, concentrations of ∆9-tetrahydrocannabinol (THC) in cannabis resin (also known as hash) have risen markedly in the past…
Persistent increased severity of cannabis use disorder symptoms in adolescents compared to adults: a one-year longitudinal study
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-024-01806-y. Article type: Research Article Keywords: Cannabis use disorder,…
The acute effects of cannabis, with and without cannabidiol, on attentional bias to cannabis related cues: a randomised, double-blind, placebo-controlled, cross-over study
Abstract Rationale: Attentional bias to drug-related stimuli is hypothesised to contribute towards addiction. However, the acute effects of Δ9-tetrahydrocannabinol (THC)…
Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study
Abstract Background: The effects of cannabis are thought to be mediated by interactions between its constituents and the endocannabinoid system.…
Cannabidiol does not attenuate acute delta‐9‐tetrahydrocannabinol‐induced attentional bias in healthy volunteers: A randomised, double‐blind, cross‐over study
Abstract Aims: To test how attentional bias and explicit liking are influenced by delta‐9‐tetrahydrocannabinol (THC) and whether these effects are…
Different Tokes for Different Folks: Use of Cannabis Products Among a Longitudinal Cohort of People with Heroin Dependence
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s11469-023-01071-5. Article type: Research Article Keywords: Cannabis, Heroin, Opioid…
Effects of cannabidiol on anandamide levels in individuals with cannabis use disorder: findings from a randomised clinical trial for the treatment of cannabis use disorder
Abstract Cannabidiol (CBD) has shown promise in treating psychiatric disorders, including cannabis use disorder – a major public health burden…