Thomas Hankemeier

December 5, 2023

A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence

Abstract Monoacylglycerol lipase (MAGL) regulates endocannabinoid 2-arachidonoylglycerol (2-AG) and eicosanoid signalling. MAGL inhibition provides therapeutic opportunities but clinical potential is…

November 15, 2023

Higher Plasma Levels of Endocannabinoids and Analogues Correlate With a Worse Cardiometabolic Profile in Young Adults

Abstract Context: The endocannabinoid system (ECS) is a signaling system composed of endocannabinoids (eCBs), their receptors, and the enzymes involved…

January 23, 2012

Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice

Abstract Background: Causes and consequences of the complex changes in lipids occurring in the metabolic syndrome are only partly understood.…