Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis
Abstract The effector B cell lymphoma-2 (BCL-2) protein BCL-2 ovarian killer (BOK) induces mitochondrial outer membrane permeabilization (MOMP) to initiate…
Taosheng Chen
An unexpected protein interaction promotes drug resistance in leukemia
Abstract The overall survival of patients with acute myeloid leukemia (AML) is poor and identification of new disease-related therapeutic targets…