Cannabigerol Exerts In Vivo and In Vitro Anti-Inflammatory Effects via Inhibition of the MAPK and NF-κB Pathways
Abstract Cannabis sativa L. has a long history of use and contains more than 80 cannabinoids. However, although cannabigerol (CBG),…
Tae-Hyung Kwon
Elevated relative humidity significantly decreases cannabinoid concentrations while delaying flowering development in Cannabis sativa L.
Abstract Introduction: Relative humidity (RH) is critical for regulating transpiration, plant morphology, and the biosynthesis of secondary metabolites in crops.…
Skin-Whitening Effects of Cannabinol (CBN) Through Melanin Inhibition in B16F10 Melanoma Cells
Abstract Melanogenesis, the key biological process underlying skin hyperpigmentation, is tightly regulated by complex molecular signaling pathways. Consequently, targeting molecular…
Cannabichromene: integrative modulation of apoptosis, ferroptosis, and endocannabinoid signaling in pancreatic cancer therapy
Abstract Cannabichromene (CBC: C21H3O2, M.W.: 314.46 g) is a non-psychotropic phytocannabinoid derived from Cannabis sativa (hemp), and its potential therapeutic…
Cannabidiol potentiates p53-driven autophagic cell death in non-small cell lung cancer following DNA damage: a novel synergistic approach beyond canonical pathways
Abstract The search for more effective and safer cancer therapies has led to an increasing interest in combination treatments that…
Cannabigerol Treatment Shows Antiproliferative Activity and Causes Apoptosis of Human Colorectal Cancer Cells
Abstract Objectives: To determine growth inhibitory and anti-cancer effects of Cannabigerol (CBG) in human colorectal cancer cells. Methods: Anti-proliferative effect…
Chromosome-level Haploid Assembly of Cannabis sativa L. cv. Pink Pepper
Abstract As molecular research on hemp (Cannabis sativa L.) continues to advance, there is a growing need for the accumulation…
Thermo-chemical conversion kinetics of cannabinoid acids in hemp (Cannabis sativa L.) using pressurized liquid extraction
Abstract Cannabinoid decarboxylation via thermo-chemical conversion has the potential to reduce the cannabinoid degradation and evaporation due to short reaction…
In Vitro and In Vivo Anti-Inflammatory Potential of Cannabichromene Isolated from Hemp
Abstract Cannabichromene (CBC), a non-psychoactive cannabinoid found in Cannabis sativa, has recently been shown to possess several medicinal properties. However,…
Metallothionein Family Proteins as Regulators of Zinc Ions Synergistically Enhance the Anticancer Effect of Cannabidiol in Human Colorectal Cancer Cells
Abstract Cannabidiol (CBD) is a chemical obtained from Cannabis sativa; it has therapeutic effects on anxiety and cognition and anti-inflammatory…