Cannabinoids and Genetic Epilepsy Models: A Review with Focus on CDKL5 Deficiency Disorder
Abstract Pediatric genetic epilepsies, such as CDKL5 Deficiency Disorder (CDD), are severely debilitating, with early-onset seizures occurring more than ten…
Simone Rochfort
A High-Throughput Method for the Comprehensive Analysis of Terpenes and Terpenoids in Medicinal Cannabis Biomass
Abstract Cannabis and its secondary metabolite content have recently seen a surge in research interest. Cannabis terpenes and terpenoids in…
The Power of Three in Cannabis Shotgun Proteomics: Proteases, Databases and Search Engines
Abstract Cannabis research has taken off since the relaxation of legislation, yet proteomics is still lagging. In 2019, we published…
Utilisation of Design of Experiments Approach to Optimise Supercritical Fluid Extraction of Medicinal Cannabis
Abstract Carbon dioxide supercritical fluid extraction (CO2 SFE) is a clean and cost-effective method of extracting cannabinoids from cannabis. Using…
A Multiple Protease Strategy to Optimise the Shotgun Proteomics of Mature Medicinal Cannabis Buds
Abstract Earlier this year we published a method article aimed at optimising protein extraction from mature buds of medicinal cannabis…
Top-Down Proteomics of Medicinal Cannabis
Abstract The revised legislation on medicinal cannabis has triggered a surge of research studies in this space. Yet, cannabis proteomics…
Optimisation of Protein Extraction from Medicinal Cannabis Mature Buds for Bottom-Up Proteomics
Abstract Medicinal cannabis is used to relieve the symptoms of certain medical conditions, such as epilepsy. Cannabis is a controlled…