The promising role of nanopore sequencing in cancer diagnostics and treatment
Abstract Cancer arises from genetic alterations that impact both the genome and transcriptome. The utilization of nanopore sequencing offers a…
Shiwei Duan
Current and future perspectives on the regulation and functions of miR-545 in cancer development
Abstract Micro ribonucleic acids (miRNAs) are a highly conserved class of single-stranded non-coding RNAs. Within the miR-545/374a cluster, miR-545 resides…
The tumor suppressor role and ceRNA network of miR-1294 in cancer
Abstract miRNAs are endogenous small RNAs that are important regulators of gene expression. miR-1294 was found to be significantly down-regulated…
Aberrant expression of microRNA-4443 (miR-4443) in human diseases
Abstract miRNA is a small endogenous RNA and an important regulator of gene expression. miR-4443 is abnormally expressed in 12…
Novel Insights into miR-944 in Cancer
Abstract Simple Summary: miR-944 is localized in intron 4 of TP63. ΔNp63 in intron 3 of TP63 recruits the transcription…
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma
Abstract Human osteosarcoma is considered a malignant tumor with poor prognosis that readily metastasizes. Tetrahydrocurcumin (THC) has been reported to…