A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1
Abstract Anti-CRISPRs (Acrs) are natural inhibitors of bacteria’s CRISPR-Cas systems, and have been developed as a safeguard to reduce the…
Shengnan Zhang
The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins
Abstract Molecular chaperones safeguard cellular protein homeostasis and obviate proteotoxicity. In the process of aging, as chaperone networks decline, aberrant…