Cancer cachexia: molecular basis and therapeutic advances
Abstract The dynamic interplay between neoplastic cells and the host has been increasingly recognized as important players in the pathogenesis…
Rui Xue
Discovery of Jaspamycin from marine-derived natural product based on MTA3 to inhibit hepatocellular carcinoma progression
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-75205-7. Article type: Research Article Keywords: MTA3, Pan-cancer, Hepatocellular…
Exercise-augmented THSD7B exhibited a positive prognostic implication and tumor-suppressed functionality in pan-cancer
Abstract Background: Breast cancer, one of the most prevalent malignancies among women worldwide, has rising incidence rates. Physical activity, particularly…
Exercise-downregulated CD300E acted as a negative prognostic implication and tumor-promoted role in pan-cancer
Abstract Background: Breast cancer ranks as one of the most prevalent malignancies among women globally, with increasing incidence rates. Physical…
Integrated pan-cancer genomic analysis reveals the role of SLC30A5 in the proliferation, metastasis, and prognosis of hepatocellular carcinoma
Abstract Background: SLC30A5, a member of the solute transporter protein family, is implicated in tumorigenesis and cancer progression. This study…
Conserved immuno‐collagenic subtypes predict response to immune checkpoint blockade
Abstract Background: Immune checkpoint blockade (ICB) has revolutionized the treatment of various cancer types. Despite significant preclinical advancements in understanding…
OTUD4: A Potential Prognosis Biomarker for Multiple Human Cancers
Abstract Background: Deubiquitinase OTU domain containing 4 (OTUD4) is initially identified as a K48-specific deubiquitinase and plays an important role…