Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring
Abstract Background: Cannabis legalization is expanding and men are the predominant users. We have limited knowledge about how cannabis impacts…
Rose Schrott
Refraining from use diminishes cannabis-associated epigenetic changes in human sperm
Abstract Cannabis use alters sperm DNA methylation, but the potential reversibility of these changes is unknown. Semen samples from cannabis…
Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin
Abstract Men consume the most nicotine and cannabis products but impacts on sperm epigenetics are poorly characterized. Evidence suggests that…
Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC)
Abstract As marijuana legalization is increasing, research regarding possible long-term risks for users and their offspring is needed. Little data…
Cannabis use and the sperm epigenome: a budding concern?
Abstract The United States is swiftly moving toward increased legalization of medical and recreational cannabis. Currently considered the most commonly…
Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm
Abstract Parental cannabis use has been associated with adverse neurodevelopmental outcomes in offspring, but how such phenotypes are transmitted is…
Cannabinoid exposure and altered DNA methylation in rat and human sperm
Abstract Little is known about the reproductive effects of paternal cannabis exposure. We evaluated associations between cannabis or tetrahydrocannabinol (THC)…