The impact of childhood trauma and cannabis use on paranoia: a structural equation model approach
Abstract Background: Childhood trauma is a well-established risk factor for psychosis, paranoia, and substance use, with cannabis being a modifiable…
Robin M. Murray
A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders
Abstract Background: Cannabis use severely affects the outcome of people with psychotic disorders, yet there is a lack of treatments.…
The impact of schizophrenia genetic load and heavy cannabis use on the risk of psychotic disorder in the EU-GEI case-control and UK Biobank studies
Abstract Background: The association between cannabis and psychosis is established, but the role of underlying genetics is unclear. We used…
Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents
Abstract Background: The link between cannabis use and schizophrenia is well-established in epidemiological studies, especially among adolescents with early-onset use.…
Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study
Abstract Background: The effects of cannabis are thought to be mediated by interactions between its constituents and the endocannabinoid system.…
Cannabis use and psychotic disorders in diverse settings in the Global South: findings from INTREPID II
Abstract Background: Cannabis use has been linked to psychotic disorders but this association has been primarily observed in the Global…
Cannabidiol does not attenuate acute delta‐9‐tetrahydrocannabinol‐induced attentional bias in healthy volunteers: A randomised, double‐blind, cross‐over study
Abstract Aims: To test how attentional bias and explicit liking are influenced by delta‐9‐tetrahydrocannabinol (THC) and whether these effects are…
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios
Abstract As countries adopt more permissive cannabis policies, it is increasingly important to identify strategies that can reduce the harmful…
Associations Between Canada’s Cannabis Legalization and Emergency Department Presentations for Transient Cannabis-Induced Psychosis and Schizophrenia Conditions: Ontario and Alberta, 2015–2019
Abstract Objective: Cannabis legalization in many jurisdictions worldwide has raised concerns that such legislation might increase the burden of transient…
Altered relationship between cortisol response to social stress and mediotemporal function during fear processing in people at clinical high risk for psychosis: a preliminary report
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-021-01318-z. Article type: Research Article Keywords: Clinical high risk,…