Sex-specific maladaptive responses to acute stress upon in utero THC exposure are mediated by dopamine
Abstract Cannabis remains by far the most consumed illicit drug in Europe. The availability of more potent cannabis has raised…
Roberto Frau
Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
Abstract Rationale: The use of synthetic cannabinoid receptor agonists (SCRAs) is growing among adolescents, posing major medical and psychiatric risks.…
Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats
Abstract Cannabis use among pregnant women is increasing worldwide along with permissive sociocultural attitudes toward it. Prenatal cannabis exposure (PCE),…
Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone
Abstract Increased legal availability of cannabis has led to a common misconception that it is a safe natural remedy for,…
Reversible Disruption of Pre-Pulse Inhibition in Hypomorphic-Inducible and Reversible CB1-/- Mice
Abstract Although several genes are implicated in the pathogenesis of schizophrenia, in animal models for such a severe mental illness…