Abstract Background: Cannabinoids such as cannabidiol (CBD) exhibit anti-inflammatory properties and have the potential to act as a therapeutic following…
Abstract The type 1 cannabinoid receptor (CB1R) mediates neurotransmitter release and synaptic plasticity in the central nervous system. Endogenous, plant-derived,…
Abstract Working memory is an executive function that orchestrates the use of limited amounts of information, referred to as working…
Abstract Cannabis sativa has gained popularity as a “natural substance”, leading many to falsely assume that it is not harmful.…
Abstract Because of the legalization of Cannabis in many jurisdictions and the trend of increasing Δ9-tetrahydrocannabinol (THC) content in Cannabis…
Abstract Positive allosteric modulation of the type 1 cannabinoid receptor (CB1R) has substantial potential to treat both neurological and immune…
Abstract Cannabis sativa contains more than 120 cannabinoids and 400 terpene compounds (i.e., phytomolecules) present in varying amounts. Cannabis is…
Abstract A growing body of evidence underlines the crucial role of GPR55 in physiological and pathological conditions. In fact, GPR55…
Abstract Sexual dimorphisms are observed in cannabinoid pharmacology. It is widely reported that female animals are more sensitive to the…
Abstract Childhood absence epilepsy (CAE) is a non-convulsive seizure disorder primarily in children characterized by absence seizures. Absence seizures consist…