Ping Qian

February 11, 2025

Development of a novel chimeric lysin to combine parental phage lysin and cefquinome for preventing sow endometritis after artificial insemination

Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s13567-025-01457-4. Article type: Research Article Keywords: Endometritis, chimeric lysin,…

January 14, 2025

Structural and functional analysis reveals the catalytic mechanism and substrate binding mode of the broad-spectrum endolysin Ply2741

Abstract The emergence of antibiotic-resistant bacteria has attracted interest in the field of endolysins. Here, we analyzed the diversity of…

October 18, 2024

A novel chimeric endolysin Cly2v shows potential in treating streptococci-induced bovine mastitis and systemic infections

Abstract Streptococcus species are important pathogens implicated in bovine mastitis, causing considerable economic losses within the global dairy industry. With…

May 1, 2023

Exploiting Broad-Spectrum Chimeric Lysin to Cooperate with Mupirocin against Staphylococcus aureus-Induced Skin Infections and Delay the Development of Mupirocin Resistance

Abstract Staphylococcus aureus often leads to severe skin infections. However, S. aureus is facing a crisis of antibiotic resistance. The…