Treatment Strategies for Painful Pelvic Floor Conditions: A Focus on the Potential Benefits of Cannabidiol
Abstract Painful conditions of the pelvic floor include a set of disorders of the pelvic region, discreetly prevalent in the…
Pierangelo Cifelli
GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol
Abstract Recently, the potential use of phytocannabinoids (pCBs) to treat different pathological conditions has attracted great attention in the scientific…
Modulation of GABAergic dysfunction due to SCN1A mutation linked to Hippocampal Sclerosis
Abstract We compared GABAergic function and neuronal excitability in the hippocampal tissue of seven sporadic MTLE patients with a patient…
Cannabinoids in the Treatment of Epilepsy: Current Status and Future Prospects
Abstract Cannabidiol (CBD) is one of the prominent phytocannabinoids found in Cannabis sativa, differentiating from Δ9-tetrahydrocannabinol (THC) for its non-intoxicating…
Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission?
Abstract γ-Aminobutyric acid type A receptors (GABAARs) are the main inhibitory mediators in the central nervous system (CNS). GABAARs are…
Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin
Abstract Cannabidivarin (CBDV) and cannabidiol (CBD) have recently emerged among cannabinoids for their potential antiepileptic properties, as shown in several…