Acceptability of cannabidiol in patients with psychosis
Abstract Background: Cannabidiol (CBD) is a promising novel candidate treatment for psychosis. It has a more benign side effect profile…
Philip McGuire
Epigenetic Mediation of AKT1 rs1130233’s Effect on Delta-9-Tetrahydrocannabinol-Induced Medial Temporal Function during Fear Processing
Abstract High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally,…
Altered relationship between cortisol response to social stress and mediotemporal function during fear processing in people at clinical high risk for psychosis: a preliminary report
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-021-01318-z. Article type: Research Article Keywords: Clinical high risk,…
Cannabidiol (CBD) as a novel treatment in the early phases of psychosis
Abstract The pharmacological interventions available for individuals in the early stages of psychosis are extremely limited. For those at clinical…
Eye movements in patients in early psychosis with and without a history of cannabis use
Abstract It is unclear whether early psychosis in the context of cannabis use is different from psychosis without cannabis. We…
A single dose of cannabidiol modulates medial temporal and striatal function during fear processing in people at clinical high risk for psychosis
Abstract Emotional dysregulation and anxiety are common in people at clinical high risk for psychosis (CHR) and are associated with…
Lack of evidence for the effectiveness or safety of over-the-counter cannabidiol products
Abstract Over the past 5 years, public interest in the potential health benefits of cannabidiol (CBD) has increased exponentially, and…
Cannabis use in patients with early psychosis is associated with alterations in putamen and thalamic shape
Abstract Around half of patients with early psychosis have a history of cannabis use. We aimed to determine if there…
Association of cannabis with glutamatergic levels in patients with early psychosis: Evidence for altered volume striatal glutamate relationships in patients with a history of cannabis use in early psychosis
Abstract The associative striatum, an established substrate in psychosis, receives widespread glutamatergic projections. We sought to see if glutamatergic indices…
Adverse effects of cannabidiol: a systematic review and meta-analysis of randomized clinical trials
Abstract Cannabidiol (CBD) is being investigated as a treatment for several medical disorders but there is uncertainty about its safety.…