Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles
Abstract DNA methylation is recognized as one of several epigenetic regulators of gene expression and as potential driver of carcinogenesis…
Peter Schirmacher
Chromosome 9p copy number gains involving PD-L1 are associated with a specific proliferation and immune-modulating gene expression program active across major cancer types
Abstract Background: Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various…