Latent Profile Analysis of Moral Sensitivity and Influencing Factors Among Nursing Students in China
Abstract Aim: This study aimed to analyse the latent profiles of moral sensitivity of nursing students and to explore the…
Peng Luo
THBS2 + cancer-associated fibroblasts promote EMT leading to oxaliplatin resistance via COL8A1-mediated PI3K/AKT activation in colorectal cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12943-024-02180-y. Article type: Research Article Keywords: Colorectal cancer, Oxaliplatin…
Comprehensive analysis of VEGF/VEGFR inhibitor-induced immune-mediated hypertension: integrating pharmacovigilance, clinical data, and preclinical models
Abstract Introduction: This study aimed to elucidate the differential immunological mechanisms and characteristics of hypertension induced by VEGF inhibitors (VEGFi)…
Association of cannabis use with depression among cancer patients
Abstract The rate of cannabis use by cancer patients is climbing. However, as the risk of mental illness caused by…
Psychiatric disorders associated with immune checkpoint inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database
Abstract Background: With the increasing use of immune checkpoint inhibitors (ICIs) for tumour immunotherapy, the immune-related adverse events (irAEs) caused…
A pan-cancer and single-cell sequencing analysis of CD161, a promising onco-immunological biomarker in tumor microenvironment and immunotherapy
Abstract Background: CD161 has been linked to the appearance and development of various cancers. Methods: The mutation map and the…
Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma
Abstract Background: The mechanism of copper-induced cellular death was newly discovered and termed cuproptosis. Inducing cuproptosis in cancer cells is…
Identify the immune characteristics and immunotherapy value of CD93 in the pan-cancer based on the public data sets
Abstract CD93 is a transmembrane receptor that is mainly expressed on endothelial cells. A recent study found that upregulated CD93…
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy
Abstract The aberrant protein disulfide isomerase A5 (PDIA5) expression was relevant to the poor prognosis of patients with human cancers.…
A Pan-Cancer Analysis Reveals CLEC5A as a Biomarker for Cancer Immunity and Prognosis
Abstract Background: CLEC5A is a member of the C-type lectin superfamily. It can activate macrophages and lead to a series…