Abstract Background: The identification of critical states during disease progression is essential yet challenging for preventing disease deterioration and developing…
Abstract Complex disease progression typically involves sudden and non-linear transitions accompanied by devastating effects. Uncovering such critical states or pre-disease…
Abstract Background: Disease progression in biosystems is not always a steady process but is occasionally abrupt. It is important but…
Abstract Objective: This study aims to identify reliable prognostic biomarkers for differentiated thyroid cancer (DTC) based on glycolysis-related genes (GRGs),…
Abstract The dynamic network biomarker (DNB) method has advanced since it was first proposed. This review discusses advances in the…
Abstract Background: Developing effective strategies for signaling the pre-disease state of complex diseases, a state with high susceptibility before the…