Anti-Neuroinflammatory Cannabinoid Acids as a New Therapeutic Approach for Multiple Sclerosis
Abstract Neuroinflammation is a hallmark of multiple sclerosis (MS). MS is marked by glial cell activation, autoreactive T cells, and…
Nirit Bernstein
The power of zinc: excess and deficiency of Zn decrease cannabinoids in cannabis without Zn toxicity concerns to consumers
Abstract Background: Some of the mineral nutrients essential for plants are heavy metals, which their consumption may involve health concerns…
Genome-wide inventory and functional characterization of cannabinoid oxidocyclases in Cannabis sativa
Authors: Minxuan Li, Sen Cai ⚬, Xu Bai, Yuzeng Ouyang, Lina Chen, Zhiyuan Zhang, Weiqi Tang, Marc Xu, Deyong Ao,…
From deficiency to toxicity: Magnesium increases cannabinoid and terpene production in cannabis plants
Abstract Background: The biological-therapeutic activity of medical cannabis is based on a wide range of secondary metabolites, including terpenes and…
Inflorescence development in female cannabis plants is mediated by photoperiod and gibberellin
Abstract In cannabis seedlings, the initiation of solitary flowers is photoperiod-independent. However, when cannabis reaches the adult stage, short-day photoperiod…
Selected cannabis cultivars modulate glial activation: in vitro and in vivo studies
Abstract Introduction: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by neuroinflammation, demyelination and…
Therapeutic Potential of Phytocannabinoid Cannabigerol for Multiple Sclerosis: Modulation of Microglial Activation In Vitro and In Vivo
Abstract Multiple sclerosis (MS) is a widespread chronic neuroinflammatory and neurodegenerative disease. Microglia play a crucial role in the pathogenesis…
Too Dense or Not Too Dense: Higher Planting Density Reduces Cannabinoid Uniformity but Increases Yield/Area in Drug-Type Medical Cannabis
Abstract A major challenge for utilizing cannabis for modern medicine is the spatial variability of cannabinoids in the plant, which…
Cannabis Extract Effects on Metabolic Parameters and Gut Microbiota Composition in a Mice Model of NAFLD and Obesity
Abstract Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver abnormalities and has been linked with metabolic…
Nitrogen Source Matters: High NH4/NO3 Ratio Reduces Cannabinoids, Terpenoids, and Yield in Medical Cannabis
Abstract The N form supplied to the plant, ammonium (NH4+) or nitrate (NO3–), is a major factor determining the impact…