Nephi Stella

January 12, 2024

A preclinical model of THC edibles that produces high-dose cannabimimetic responses

Abstract No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ9-tetrahydrocannabinol (THC) and its intoxicating effects,…

March 6, 2023

Pharmacological characterization of the endocannabinoid sensor GRABeCB2.0

Abstract Introduction: The endocannabinoids (eCBs), 2-arachidonoylglycerol (2-AG) and arachidonoyl ethanolamine (AEA), are produced by separate enzymatic pathways, activate cannabinoid receptors…

January 1, 2021

Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome

Abstract Dravet Syndrome (DS) is a severe childhood epilepsy caused by heterozygous loss-of-function mutations in the SCN1A gene encoding brain…