Pan-cancer analysis of whole-genome doubling and its association with patient prognosis
Abstract Background: Whole-genome doubling (WGD) is a common mutation in cancer. Various studies have suggested that WGD is associated with…
Mikita Suyama
Pan‐cancer analysis of mutations in open chromatin regions and their possible association with cancer pathogenesis
Abstract Background: Open chromatin is associated with gene transcription. Previous studies have shown that the density of mutations in open…
Pan-cancer analysis of non-coding recurrent mutations and their possible involvement in cancer pathogenesis
Abstract Cancer-related mutations have been mainly identified in protein-coding regions. Recent studies have demonstrated that mutations in non-coding regions of…
Pan-cancer analysis of intratumor heterogeneity associated with patient prognosis using multidimensional measures
Abstract Human cancers accumulate various mutations during development and consist of highly heterogeneous cell populations. This phenomenon is called intratumor…