Miao Zhang

April 23, 2026

PRDM16 Drives Thyroid Cancer Differentiation via a TRIM58-MVP Axis to Suppress MAPK and PI3K/AKT Signaling

Abstract Thyroid cancer frequently undergoes dedifferentiation, progressing into poorly differentiated or anaplastic carcinoma, which is characterized by therapeutic resistance and…

March 26, 2025

Multi-omics pan-cancer analysis reveals the diagnostic and prognostic value of C8orf76, with experimental validation of its impact on lung adenocarcinoma cell proliferation

Abstract Background: Chromosome 8 open reading frame 76 (C8orf76) is a nuclear protein-encoding gene, has received limited attention in current…