Abstract The tumor microenvironment (TME) and activated angiogenesis in thyroid carcinoma (TC) are critical for tumor growth and metastasis. Nuclear…
Abstract Intratumor heterogeneity (ITH) is a biomarker of tumor progression, metastasis, and immune evasion. Previous studies evaluated ITH mostly based…
Abstract Background: Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have…
Abstract Background: PLK1 overexpression is oncogenic and is associated with poor prognosis in various cancers. However, the current PLK1 inhibitors…
Abstract Background: The Cancer Genome Atlas (TCGA) is an important data resource for cancer biologists and oncologists. However, a lack…
Abstract The homogeneity and heterogeneity in somatic mutations, copy number alterations and methylation across different cancer types have been extensively…