Integrative omics analyses broaden treatment targets in human cancer
Abstract Background: Although large-scale, next-generation sequencing (NGS) studies of cancers hold promise for enabling precision oncology, challenges remain in integrating…
Matthew A. Wyczalkowski
Driver Fusions and Their Implications in the Development and Treatment of Human Cancers
Abstract Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across…