Dynamics of gut metabolome and microbiota maturation during early life
Abstract Early-life gut microbiome-metabolome crosstalk plays a crucial role in maintaining host physiology. The microbially produced metabolites often convey effects…
Matej Orešič
Novel Lipid Formulation Increases Absorption of Oral Cannabidiol (CBD)
Abstract Background: Cannabidiol (CBD) is an approved treatment for childhood epilepsies and a candidate treatment for several other CNS disorders.…
Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study
Abstract Background: The effects of cannabis are thought to be mediated by interactions between its constituents and the endocannabinoid system.…
Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species
Abstract Knowledge about in vivo effects of human circulating C-6 hydroxylated bile acids (BAs), also called muricholic acids, is sparse.…
Links between central CB1-receptor availability and peripheral endocannabinoids in patients with first episode psychosis
Abstract There is an established, link between psychosis and metabolic abnormalities, such as altered glucose metabolism and dyslipidemia, which often…
Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography–tandem mass spectrometry
Abstract Electronic supplementary material: The online version of this article (10.1007/s00216-019-02263-6) contains supplementary material, which is available to authorized users.…