Mario Vitale

August 18, 2025

Inhibition of Metalloproteinases-2, -9, and -14 Suppresses Papillary Thyroid Carcinoma Cell Migration and Invasion

Abstract Papillary thyroid carcinoma (PTC), while often having a favorable prognosis, can progress to aggressive forms. Matrix metalloproteinases (MMPs) are…

June 5, 2025

Integrin–fibronectin interaction is a pivotal biological and clinical determinant in papillary thyroid carcinoma

Abstract Integrins influence tumor growth, metastasis, and angiogenesis, making them potential targets for therapeutic intervention. In this study, we analyzed…

June 11, 2021

Higher Integrin Alpha 3 Beta1 Expression in Papillary Thyroid Cancer Is Associated with Worst Outcome

Abstract Simple Summary: Integrins are cell-extracellular matrix adhesion molecules considered functionally related to the development of cancer metastasis. Starting from…