A Numb–Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer
Abstract Numb regulates the activity of the tumor suppressor p53 by inhibiting Mdm2. This study from Colaluca et al. highlights…
Marina Mapelli
Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain
Abstract Myosin VI functions in endocytosis and cell motility. Alternative splicing of myosin VI mRNA generates two distinct isoform types,…